Tramadol 100mg is an exceptional pain reliever, which is categorized under the narcotic class of medicine. It comes in several types of forms like extend released and quick released, which is used to combat the moderate to severe pain. It is considered as one of the most admired drug among the pain killers. Tramadol has a harmful effect in large amount, but it is safe in moderate doses like Tramadol 100mg. Even though, Tramadol comes under the narcotic analgesic class, but still has the least habit forming quality. Tramadol is also useful in pain which occurs due to the surgery and extreme types of injuries etc.
Generic Tramadol is a modulator of several types of receptors which are responsible for the pain; these receptors are serotonin reuptake inhibitor, NMDA receptor antagonist and μ-opioid receptor agonist etc. Tramadol mainly works on μ-opioid receptor and helps to decrease the pain. It has two different types of mechanism which are involved in reducing the pain. The mechanism which is associated to reduce the pain is binding with μ-opioid receptor and other is to diminish the effects of reuptake of serotonin and norepinephrine. Generally, μ-opioid receptors are found ubiquitously in human bodies which are responsible for the occurrence of pain. Tramadol binds with these receptors and reduces the effects of chemicals like prostaglandins, COX1 and COX2 etc. This mechanism helps to decrease pain in very short time. Serotonin and norepinephrine neurotransmitter are responsible for reducing the pain.
The availability of Tramadol is depends upon in various forms such as it is marketed as in immediate-release tablet which lasts from 4 to 6 hours, extended-release version which taken only once for decreasing the pain, etc.
Safety of any type of narcotic substance is depends upon the individual's tolerability. Tramadol is always stared from the lower dose that is Tramadol 100mg. The highest tolerable dose of Tramadol is 450mg in a day. Tramadol is directly act on the central nervous system and help to improve the pain.
Condition which are contraindicated along with the use of Tramadol 100mg:
Contraindications are divided into two classes such as
1. Absolute Contraindications: These contraindications are those conditions in which the consumption of Tramadol 100mg must be avoided at any cost such as:
2. Relative Contraindications: In these types of contraindications simultaneous intake of Tramadol 100mg should be avoided:
Missed does: In case of missed dose take it as soon as possible. If it the time of the next dose then skip to take the missed dose.
Overdose: Overdose of the drug produces some does effects so avoid the drug in extra amount. If you take overdose by mistake then contact with doctor immediate.
The most common side effects experiential with Tramadol 100mg include nausea, vomiting, dizziness, dry mouth, and sedation. These are generally well-tolerated and do not require any dose modification. But there are some severe sides effects are occurred such as:
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